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Doxepin Capsules, 50mg - US 8916

Doxepin Capsules, 50mg - US 8916

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Prescription Behavior and Allergy Capsules for Dogs and Cats

Product Description

Doxepin HCl 50mg Capsules are a prescription tricyclic antidepressant with strong antihistamine properties used off-label by vets for dogs and cats. Working through dopamine and histamine receptor activity in the brain and body, it eases anxiety-driven behavioral issues and relieves chronic allergic itching at the same time. The 50mg strength suits medium-sized dogs needing a precise intermediate dose for anxiety, depression, compulsive disorders, or pruritic skin conditions.

Benefits

  • Anxiety and Depression Relief: Helps reduce depression, general anxiety, fear-based reactions, and noise phobia distress in dogs and cats.
  • Chronic Itch Management: Brings antihistamine relief for long-lasting allergic itching and skin inflammation in pets that have not improved on standard treatments.
  • Compulsive Grooming Control: Reduces psychogenic overgrooming, excessive licking, and self-traumatic behavior driven by compulsive or anxiety-related disorders in pets.
  • Dual-Action Formula: Goes after both central nervous system pathways and peripheral histamine receptors to handle behavioral and skin conditions together.
  • Intermediate Dose Flexibility: The 50mg strength offers a practical middle-range option between lower and higher capsule strengths for accurate weight-based dosing.

Ingredients

Active Ingredients

Doxepin Hydrochloride

How to Use

Doxepin HCl 50mg Capsules are a prescription-only medication. A valid veterinarian prescription is required to purchase this product.

Please follow your veterinarian's specific instructions for the dosage and administration of this medication for your pet.

Disclaimer: Dosage and administration of this medication must be determined by a licensed veterinarian. Always consult your veterinarian before administering or adjusting any prescription medication for your pet.

Tucking the capsule inside a soft pill pocket or pill wrap treat makes giving this medication easy and stress-free for both you and your pet. The capsule may be given with or without food, but if your pet experiences vomiting on an empty stomach, offer the capsule with a small meal going forward. Make sure your pet always has fresh water nearby while taking this medication.

Shop Pill Pockets for Dogs | Shop Pill Pockets for Cats

Additional Information

Precautions

  • Avoid With MAOIs: Keep away from pets that received selegiline or amitraz in the past 14 days as a dangerous drug interaction can follow.
  • No Amitraz Flea Collars: Amitraz tick and flea collars must never be worn during doxepin treatment due to the serious toxic interaction risk they carry.
  • Avoid Tyramine-Rich Foods: Aged cheeses and high-tyramine foods must stay off the menu completely as they can set off a dangerous blood pressure spike.
  • Avoid in Glaucoma: Do not give to pets with glaucoma or urinary retention as doxepin can make both of these conditions noticeably worse over time.
  • Caution in Seizures: Use very carefully in pets with any prior seizure history as doxepin can lower the threshold at which seizures occur.
  • Caution in Thyroid Disease: Avoid in hyperthyroid pets as dangerous interactions between doxepin and elevated thyroid hormones can develop during treatment.
  • Drug Interaction Risk: Tell your vet if the pet takes cimetidine, fluoxetine, estrogens, sedatives, enalapril, verapamil, or ranitidine before starting doxepin.

Possible Side Effects

  • Drowsiness and Sedation: Sleepiness tends to ease as the pet settles in; it is the most commonly reported reaction during doxepin treatment.
  • Dry Mouth and Constipation: Anticholinergic effects causing dry mouth and reduced bowel motility are commonly observed in pets receiving doxepin.
  • Blue-Green Urine: Urine may turn blue-green in some pets on doxepin; this is a harmless metabolic effect that clears up once treatment stops.
  • GI Upset and Excitability: Some pets get unusually wound up or have stomach issues like vomiting when first starting out on doxepin.
  • Serious Cardiac Effects: Overdosing can trigger dangerous heart rhythm problems that need emergency veterinary attention as soon as they appear.

Storage Information

  • Room Temperature Storage: Keep capsules in a sealed container at a steady temperature between 68°F and 77°F, well away from heat and moisture.
  • Protect From Light: Sunlight and damp spots can break down the capsules over time, so keep them somewhere cool, dark, and dry.
  • Keep Out of Reach: Put this medication somewhere children and untreated pets cannot get to it on their own.

Note: For generic medications, the product image shown may not reflect the actual item received. Generic medications can vary in size, color, and shape between orders depending on the manufacturer. Additionally, your medication may arrive packaged in a HardyPaw Pharmacy vial.

Shipping & Return

We offer ground, express, and priority delivery; see our shipping policy for details.

For return instructions or product concerns, please refer to our detailed refund policy.

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.

Frequently Asked Questions

Q1: What makes doxepin an effective antihistamine for pets with allergic skin conditions?

Ans: Doxepin is one of the strongest H1 antihistamines in veterinary medicine, blocking histamine far more effectively than everyday options like diphenhydramine. Vets turn to it for pets stuck in a cycle of chronic allergic itching that has not budged with standard antihistamine options already tried.

Q2: Can doxepin be prescribed for cats with anxiety and overgrooming?

Ans: Yes, doxepin is used off-label in cats for anxiety-driven overgrooming, psychogenic alopecia, and behavioral disorders. Cats process medications differently from dogs, so dosing for cats can look quite different. The vet sets the right amounts and intervals for each individual cat rather than applying standard dog dosing.

Q3: Does doxepin interact with any common flea and tick prevention products?

Ans: Amitraz-based flea and tick collars must never be used on pets taking doxepin as amitraz acts like an MAOI and the combination can turn dangerous. Most spot-on and oral options like fipronil, imidacloprid, and afoxolaner are safe, but always check with the vet before putting any new parasite product on a pet receiving doxepin.

Q4: How is the correct doxepin dose determined for a dog or cat?

Ans: The dose is based on body weight, with dogs typically getting anywhere from 0.25 to 2.5 mg per pound depending on what is being treated. The 50mg capsule tends to work well for medium-sized dogs. The vet works out the exact amount and picks the right capsule strength for each pet individually.

Q5: Should doxepin be tapered gradually when stopping treatment in pets?

Ans: Yes, stopping doxepin suddenly can bring on withdrawal effects like nausea, agitation, and behavioral shifts, so a gradual taper is the right approach. How long the taper takes depends on the dose and how long the pet has been on it. Never reduce or stop this medication without first checking with the vet.

This Shipping Policy explains how orders are processed, shipped, tracked, and delivered.

1. Shipping Origin and Fulfillment

Orders are dispatched from our U.S.-based fulfillment center. We deliver to eligible addresses within the United States and to eligible international destinations shown at checkout.

If a destination, shipping service, or product is not eligible for delivery, checkout will not offer that shipping option.

2. Order Processing Time

Orders are generally processed within 1–5 business days before shipment. Processing time is separate from carrier transit time.

Our order cut-off time is 6:00 PM Pacific Time (PT). Orders placed after the cut-off time, on weekends, or on applicable holidays begin processing on the next business day.

Processing may include order verification and preparation for shipment.

3. U.S. Shipping Methods, Costs, and Transit Times

For eligible U.S. addresses, our current shipping options are:

  • Priority Shipping: $5.99 — estimated carrier transit time of 1–2 business days after shipment.
  • Standard Shipping: $2.99 — estimated carrier transit time of 3–6 business days after shipment.
  • Free Shipping: $0 — estimated carrier transit time of 5–8 business days after shipment.

Total estimated delivery time includes both the 1–5 business day processing period and the applicable carrier transit time. The shipping service, cost, and delivery estimate available for your order are shown at checkout before payment.

4. International Shipping

We ship to eligible international destinations. Available international shipping services, shipping charges, and estimated delivery times vary by destination and are displayed at checkout.

For eligible international orders, applicable import duties and taxes are calculated and collected at checkout where required. When these charges apply, the order is shipped on a duties-and-taxes-paid basis so that the same import charges should not be collected again at delivery.

International delivery estimates may be affected by carrier operations, customs processing, local holidays, weather, or other events outside normal transit conditions.

5. Tracking

When tracking is available, you will receive shipment confirmation with tracking information after the order has shipped. Please allow up to 48 hours for tracking information to become active after the carrier receives the shipment.

6. Address Accuracy and Changes

Please review your shipping address carefully before submitting an order. If you notice an address error, contact us as soon as possible. We will try to help before shipment, but an address change cannot be guaranteed once fulfillment or carrier processing has begun.

Additional carrier or re-delivery charges resulting from an incorrect or incomplete address may be the customer's responsibility where permitted by law.

7. Delayed or Lost Shipments

If your shipment has not arrived within the estimated delivery timeframe, please contact us. We will review the tracking information, work with the carrier when necessary, and assist with an appropriate resolution based on the circumstances.

Delivery estimates are not guarantees and may be affected by carrier delays, weather, public holidays, customs processing, or other transportation disruptions.

8. Damaged, Defective, or Incorrect Deliveries

If an item arrives damaged, defective, or incorrect, contact us within 7 calendar days after confirmed delivery. Please include your order number and clear photos of the item, packaging, and shipping label when relevant.

Approved cases are handled under our Return & Refund Policy, including return-shipping assistance when the issue is our responsibility.

9. Policy Updates

We may update this Shipping Policy when our shipping services or operating requirements change. The current version will be posted on this page.

10. Contact Us

If you have questions about shipping or an order in transit, please use our Contact page or the current contact information displayed in the website footer.

This Return & Refund Policy explains when a return is eligible, how to send an item back, who pays return shipping, and how approved refunds are processed.

1. Return Window

You may request an eligible return within 30 days after confirmed delivery. Return requests submitted after the 30-day period are not accepted unless applicable law requires otherwise.

2. Return Eligibility

To qualify for a standard return, the item must generally be:

  • Unused, unwashed, and in its original condition.
  • Returned with the original packaging, tags, accessories, manuals, and other included components, when applicable.
  • Not specifically identified as final sale or non-returnable before purchase.

Products that show use, alteration, avoidable damage, missing components, or other conditions outside the eligibility requirements may be ineligible for a refund.

3. Product-Specific Non-Returnable Items

Some products may be non-returnable for hygiene, safety, customization, final-sale, or other product-specific reasons. Any such restriction will be disclosed on the product page or before purchase when applicable.

4. No Direct Exchanges

We do not provide direct exchange service. If you want a different item, size, color, model, or version, return the eligible original item under this Policy and place a new order separately.

5. How to Start a Return

Returns are handled by mail. Before sending an item back, contact our customer support team through the Contact page or the current contact information displayed in the website footer. Please provide:

  • Your order number.
  • The item or items you want to return.
  • The reason for the return.

Returns sent without required return authorization may be delayed or refused.

6. Prepaid Return Label and Return Shipping Cost

For eligible mail returns, a prepaid return label is included in the package.

For a standard return made for customer-choice reasons, the actual carrier postage charged for use of the prepaid return label will be deducted from the approved refund. We do not charge a separate restocking fee.

If the return is required because the item arrived damaged, defective, or incorrect and the claim is approved, we cover the return-label cost.

If you choose not to use the provided label when an alternative return method is authorized, use a trackable shipping service and keep your shipping receipt until the return is completed.

7. Original Shipping Charges

Original outbound shipping charges are non-refundable for standard customer-choice returns, except where required by law. If the return results from an approved damaged, defective, or incorrect item, applicable shipping charges will be handled as part of the resolution.

8. Refund Review and Processing

After the returned item is received, we inspect it and notify you whether the refund is approved.

If approved, the refund is issued to the original payment method. We generally process an approved refund within 1–3 business days. After the refund is issued, your bank or card provider may require an additional 5–10 business days to post the funds to your account.

9. Damaged, Defective, or Incorrect Items

If an item arrives damaged, defective, or incorrect, contact us within 7 calendar days after confirmed delivery. Include your order number and clear photos of the item, packaging, and shipping label when relevant.

After review, we will provide an appropriate resolution. When a return is required for an approved claim, we cover the return shipping cost.

10. Refused or Undeliverable Shipments

If a shipment is refused or returned because of incorrect or incomplete customer-provided shipping information, actual carrier return, re-delivery, or related shipping charges may be deducted from an otherwise eligible refund where permitted by law.

11. Policy Updates

We may update this Return & Refund Policy when our return procedures or legal requirements change. The current version will be posted on this page.

12. Contact Us

If you need help with a return or refund, please use our Contact page or the current contact information displayed in the website footer.

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